Wednesday, May 09, 2007

Chapter 3 Schizophrenia

From: Public Health Agency of Canada


Highlights

  • Schizophrenia affects 1% of the Canadian population.
  • Onset is usually in early adulthood.
  • Schizophrenia can be treated effectively with a combination of medication, education, primary care services, hospital-based services and community support, such as housing and employment.
  • Fifty-two percent of hospitalizations for schizophrenia in general hospitals are among adults 25-44 years of age.
  • Hospitalization rates for schizophrenia in general hospitals are increasing among young and middle-aged men.

What Is Schizophrenia?

Schizophrenia is a brain disease and one of the most serious mental illnesses in Canada. Common symptoms are mixed-up thoughts, delusions (false or irrational beliefs), hallucinations (seeing or hearing things that do not exist) and bizarre behaviour. People suffering from schizophrenia have difficulty performing tasks that require abstract memory and sustained attention.

All the signs and symptoms of schizophrenia vary greatly among individuals. There are no laboratory tests to diagnose schizophrenia. Diagnosis is based solely on clinical observation. For a diagnosis of schizophrenia to be made, symptoms must be present most of the time for a period of at least 1 month, with some signs of the disorder persisting for 6 months. These signs and symptoms are severe enough to cause marked social, educational or occupational dysfunction. The Canadian Psychiatric Association has developed guidelines for the assessment and diagnosis of schizophrenia.1

Symptoms
Schizophrenia
  • Delusions and/or hallucinations
  • Lack of motivation
  • Social withdrawal
  • Thought disorders

How Common Is Schizophrenia?

The prevalence of schizophrenia in the general population is estimated to vary between 0.2% and 2%, depending upon the measures used. However, a prevalence rate of 1% is generally accepted as the best estimate.2

Impact of Schizophrenia

Who Is Affected by Schizophrenia?

The onset of schizophrenia typically occurs between the late teens and mid-30s. Onset before adolescence is rare. Men and women are affected equally by schizophrenia, but men usually develop the illness earlier than women. If the illness develops after the age of 45, it tends to appear among women more than men, and they tend to display mood symptoms more prominently.

Ideally, data from a population survey would provide information on the age/sex distribution of individuals with schizophrenia. Statistics Canada's Canadian Community Health Survey (CCHS) will provide data on the prevalence of self-reported schizophrenia in the future. This will likely underestimate the true prevalence, however, since the survey team will not reach those individuals with schizophrenia who are homeless, in hospital or in supervised residential settings.

Although most individuals with schizophrenia are treated in the community, hospitalization is sometimes necessary to stabilize symptoms. At the present time, hospitalization data provide the best available, though limited, description of individuals with schizophrenia.

In 1999, rates of hospitalization for schizophrenia in general hospitals varied with age (Figure 3-1). Rates among men increased dramatically in the 20-24 year age group and remained high before beginning to decrease among 40-44 year olds. The pattern among women showed a gradual increase in hospitalizations to a peak between 35 and 49 years, after which it showed a steady decline. Men had much higher rates than women until the age of 50, after which rates among women were slightly higher.

Figure 3-1 Hospitalizations for schizophrenia* in general hospitals per 100,000 by age group, Canada, 1999/2000

How Does It Affect Them?

Schizophrenia has a profound effect on an individual's ability to function effectively in all aspects of life - self-care, family relationships, income, school, employment, housing, community and social life.3

The high rates of hospitalization among young and middle-aged men and women highlight the effect of schizophrenia on people who are in their most productive years - a time when most people are forming families, establishing careers, and generally "building equity" in their lives.

Early in the disease process, people with schizophrenia may lose their ability to relax, concentrate or sleep and they may withdraw from friends. Performance at work or school often suffers. With effective early treatment to control symptoms, individuals can prevent further symptoms and optimize their chance of leading full, productive lives.

The onset of schizophrenia in the early adulthood years usually leads to disruptions in an individual's education. Individuals with schizophrenia often find it difficult to maintain employment for a sustained period of time.

Although some individuals have healthy relationships, the majority with schizophrenia (60% to 70%) do not marry, and most have limited social contacts.4 The chronic course of the disorder contributes to ongoing social problems. As a result, individuals with schizophrenia are greatly over-represented in prison and homeless populations.4

Up to 80% of individuals with schizophrenia will abuse substances during their lifetime. Substance abuse is associated with poor functional recovery, suicidal behaviour and violence.1

The responsibility for primary care of an individual with schizophrenia usually falls on the shoulders of the family. This has many implications. Not only are the family's normal activities disrupted, but family members must also cope with the unpredictability of the individual affected, the side effects of the medication, and the frustration and worry about the future of their loved one. In times of crisis, the decision whether to admit the individual to hospital involuntarily is one of the most difficult dilemmas that a family may face. The family often has to deal with the stigma attached to schizophrenia.

The mortality associated with schizophrenia is one of the most distressing consequences of the disorder. Approximately 40% to 60% of individuals with schizophrenia attempt suicide, and they are between 15 to 25 times more likely than the general population to die from a suicide attempt.5 Approximately 10% will die from suicide.

Economic Impact

Schizophrenia places a substantial financial burden on individuals with the illness, the members of their family and the health care system. In 1996, the total direct cost of schizophrenia in Canada was estimated to be $2.35 billion, or 0.3% of the Canadian Gross Domestic Product.6 This includes health care costs, administrative costs of income assistance plans, value of lost productivity, and incarceration costs attributable to schizophrenia. The indirect costs of schizophrenia are estimated to account for another $2 billion yearly. Globally, nearly 3% of the total burden of human disease is attributed to schizophrenia.7

Stigma Associated with Schizophrenia

Public misunderstanding and fear contribute to the serious stigma associated with schizophrenia. Contrary to popular opinion, most individuals with the disorder are withdrawn and not violent. Nonetheless, the stigma of violence interferes with an individual's ability to acquire housing, employment and treatment, and also compounds difficulties in social relationships. These stereotypes also increase the burden on families and care givers.

Causes of Schizophrenia

Historically, a number of psychological hypotheses were advanced to account for schizophrenia. Today medical science recognizes schizophrenia as a disease of the brain. Although the exact cause is unknown, it is likely that a functional abnormality in neurotransmitters produces the symptoms of the illness. This abnormality may be either the consequence or the cause of structural brain abnormalities.8

A combination of genetic and environmental factors is considered to be responsible for the development of this functional abnormality. These factors appear to affect the development of the brain at critical stages during gestation and after birth.

Genetic Influence

Immediate family members of individuals with schizophrenia are 10 times more likely than the general population to develop schizophrenia, and children of two parents with schizophrenia have a 40% chance of developing the disorder.3

Environmental Factors

Although the evidence to date is inconclusive, potential environmental contributions to the development of schizophrenia include prenatal or perinatal trauma, season and place of birth, and viral infections. While studies have established a link between severe social disadvantage and schizophrenia, the results suggest that social factors do not cause schizophrenia, but rather the reverse may be true: poor social circumstances are likely a result of the disorder.2

Treatment of Schizophrenia

Unfortunately, given our state of knowledge, methods for preventing schizophrenia remain unknown. Minimizing the impact of this serious illness depends mainly on early diagnosis, appropriate treatment and support.

Schizophrenia differs from other mental illnesses in the intensity of care that it requires. A comprehensive treatment program includes1:

  1. Antipsychotic medication, which forms the cornerstone of treatment for schizophrenia
  2. Education of the individual about his / her illness and treatment
  3. Family education and support
  4. Support groups and social skills training
  5. Rehabilitation to improve the activities of daily living
  6. Vocational and recreational support
  7. Cognitive therapy9
  8. Integrated addictions program10

The course of schizophrenia varies, but in most cases it involves recurrent episodes of symptoms. Although available pharmacological treatments can relieve many of the symptoms, most people with schizophrenia continue to suffer some symptoms throughout their lives.

Appropriate treatment early in the course of the disease and adherence to continued and adequate treatment are essential to avoiding relapses and preventing hospitalization. During periods of remission, whether spontaneous or due to treatment, the individual may function well. Newer medications (and improved dosage guidelines for older medications) have substantially reduced the prevalence of severe neurological side effects that were once commonly associated with long-term pharmacological treatment of schizophrenia.

Optimizing the functional status and wellbeing of individuals with schizophrenia requires a supportive family and wide range of services, including institutional, community, social, employment and housing services. Ideally, multidisciplinary community treatment teams provide these services.

Social skills training strives to improve social functioning by working with individuals to resolve problems with employment, leisure, relationships and activities of daily life.

Occasionally, however, timely admission to hospital to control symptoms may prevent the development of more severe problems. Canadian hospitalization data provide insight into the use of hospital services as one of the treatment modalities.

In 1999, in the younger age groups with schizophrenia, the disorder was the diagnosis most responsible for determining their length of stay in hospital (Figure 3-2). In older age groups (65+ years), schizophrenia was more likely to be an associated condition.

Figure 3-2 Hospitalizations for schizophrenia in general hospitals per 100,000 by contribution to length of stay and age group, Canada, 1999/2000

Between 1987 and 1999, hospitalizations for schizophrenia increased slightly among women (3%), but they increased dramatically among men (28%) (Figure 3- 3).

Figure 3-3 Rates of hospitalization for schizophrenia* in general hospitals by sex, Canada, 1987/88-1999/2000 (standardized to 1991 Canadian population)

Hospitalization rates among women aged 45-64 and 65+ years demonstrated a slight increase between 1987 and 1999 (Figure 3-4). Rates among women aged between 25 and 44 years decreased during the same period.

Figure 3-4 Rates of hospitalization for schizophrenia* among women in general hospitals, Canada, 1987/88- 1999/2000 (standardized to 1991 Canadian population)

Hospitalization rates for schizophrenia rose among men in all age groups from 15 to 64 years between 1987 and 1999 (Figure 3- 5).

Figure 3-5 Rates of hospitalization for schizophrenia* among men in general hospitals, Canada, 1987/88-1999/2000 (standardized to 1991 Canadian population)

In 1999, the average length of stay in general hospitals due to schizophrenia was 26.9 days - a decrease of 26% since 1987 (Figure 3-6).

Figure 3-6 Average length of stay in general hospitals due to schizophrenia*, Canada, 1987/88-1999/2000

Discussion of Hospitalization Data

The high hospitalization rates for schizophrenia among young adults support the clinical finding that the onset of schizophrenia typically occurs in adolescence and early adulthood. Higher rates among young men than young women agree with the observation that although schizophrenia affects both men and women, men develop it at an earlier age. Assessing whether the illness affects men differently than women in such a way that they require more hospitalization needs further research.

The increasing hospitalization rates for schizophrenia in general hospitals among young and middle-aged men may reflect, in part, the loss of psychiatric hospital beds that provided care for these men before deinstitutionalization. This care has now shifted to general hospitals. More research is needed to determine whether this also reflects shortcomings in the community treatment of the disease requiring hospitalization in order to control symptoms.

The length of stay in hospital associated with schizophrenia has decreased since 1995. This may reflect either improved treatment or the effect of decreases in hospital funding, which put pressure on the institutions to discharge people earlier than in previous years. Discharging people too early could be contributing to the increase in hospitalization rates through the need for re-admissions. Further research is needed to understand both the reason for this trend and its impact on individuals.

Future Surveillance Needs

Schizophrenia is a very serious mental illness with major ramifications for individuals and families, causing not only a great deal of personal distress but also impairment of social and occupational functioning. Fortunately, schizophrenia can be treated effectively.

Existing data provide a very limited profile of schizophrenia in Canada. The available hospitalization data need to be complemented with additional data to fully monitor this illness in Canada. Priority data needs include:

  • Incidence and prevalence of schizophrenia by age, sex and other key variables (for example, socioeconomic status, education and ethnicity).
  • Impact of schizophrenia on the quality of life of the individual and family.
  • Access to and use of health care services and community-based programs.
  • Treatment outcomes.
  • Access to community supports, such as housing, employment and education.
  • Impact of schizophrenia on the workplace and the economy.
  • Stigma associated with schizophrenia.
  • Exposure to known or suspected risk and protective factors.

References

  1. Canadian Psychiatric Association. Canadian clinical practice guidelines for the treatment of schizophrenia. Can J Psychiatry 1998;43:Supp2.
  2. Hafner H, an der Heiden W. Epidemiology of schizophrenia. Can J Psychiatry 1997;42:139-51.
  3. Keks N, Mazumdar P, Shields R. New developments in schizophrenia. Aust Fam Physician 2000;29:129-31,135-6.
  4. http://www.nimh.nih.gov/publicat/schizoph.cfm.
  5. Radomsky ED, Haas GI, Mann JJ, Sweeny JA. Suicidal behaviour in patients with schizophrenia and other psychotic disorders. Am J Psychiatry 1999;156:1590-5.
  6. Goeree R, O'Brien BJ, Goering P, Blackhouse G, Agro K, Rhodes A, Watson J. The economic burden of schizophrenia in Canada. Can J Psychiatry 1999;44:464-72.
  7. Murray CJL, Lopez AD (Eds.). The Global Burden of Disease. Cambridge, Mass: Harvard School of Public Health, 1996.
  8. Cornblatt, BA, Green MF, Walker EF. Schizophrenia: etiology and neurocognition. Millon T, Blaneyu PH, Davis R, eds. Oxford Textbook of Psychopathology. New York: Oxford University Press, 1999: 292.
  9. Norman RM, Townsend LA. Cognitive behaviour therapy for psychosis: a status report. Can J Psychiatry 1999;44:245-252.
  10. Drake RE, Mueser KT. Managing comorbid schizophrenia and substance abuse. Current Psychiatry Reports 2001;3(5):418-422.

Friday, May 04, 2007

Chapter 2 Mood Disorders

From: Public Health Agency of Canada

Highlights

  • Mood disorders include major depression, bipolar disorder (combining episodes of both mania and depression) and dysthymia.
  • Approximately 8% of adults will experience major depression at some time in their lives. Approximately 1% will experience bipolar disorder.
  • The onset of mood disorders usually occurs during adolescence.
  • Worldwide, major depression is the leading cause of years lived with disability, and the fourth cause of disability-adjusted life years (DALYs).
  • Mood disorders have a major economic impact through associated health care costs as well as lost work productivity.
  • Most individuals with a mood disorder can be treated effectively in the community. Unfortunately, many individuals delay seeking treatment.
  • Hospitalizations for mood disorders in general hospitals are approximately one and a half times higher among women than men.
  • The wide disparity among age groups in hospitalization rates for depression in general hospitals has narrowed in recent years, because of a greater decrease in hospitalization rates in older age groups.
  • Hospitalization rates for bipolar disorder in general hospitals are increasing among women and men between 15 and 24 years of age.
  • Individuals with mood disorders are at high risk of suicide.

What Are Mood Disorders?

Mood disorders may involve depression only (also referred to as "unipolar depression") or they may include manic episodes (as in bipolar disorder, which is classically known as "manic depressive illness"). Individuals with mood disorders suffer significant distress or impairment in social, occupational, educational or other important areas of functioning.

Individuals with depression feel worthless, sad and empty to the extent that these feelings impair effective functioning. They may also lose interest in their usual activities, experience a change in appetite, suffer from disturbed sleep or have decreased energy.

Individuals with mania are overly energetic and may do things that are out of character, such as spending very freely and acquiring debt, breaking the law or showing lack of judgement in sexual behaviour. These symptoms are severe and last for several weeks, interfering with relationships, social life, education and work. Some individuals may appear to function normally, but this requires markedly increased effort as time with the illness progresses.

Both depressive and manic episodes can change the way an individual thinks and behaves, and how his/her body functions.

Major depressive disorder is characterized by one or more major depressive episodes (at least 2 weeks of depressed mood or loss of interest in usual activities accompanied by at least four additional symptoms of depression).1

Bipolar disorder is characterized by at least one manic or mixed episode (mania and depression) with or without a history of major depression.2

Dysthymic disorder is essentially a chronically depressed mood that occurs for most of the day for more days than not over a period of at least two years,1 without long, symptomfree periods. Symptom-free periods last no longer than 2 months. Adults with the disorder complain of feeling sad or depressed, while children may feel irritable. The required minimum duration of symptoms for diagnosis in children is 1 year.

Symptoms
Depression Mania
  • Feeling worthless, helpless or hopeless
  • Loss of interest or pleasure (including hobbies or sexual desire)
  • Change in appetite
  • Sleep disturbances
  • Decreased energy or fatigue (without significant physical exertion)
  • Sense of worthlessness or guilt
  • Poor concentration or difficulty making decisions
  • Excessively high or elated mood
  • Unreasonable optimism or poor judgement
  • Hyperactivity or racing thoughts
  • Decreased sleep
  • Extremely short attention span
  • Rapid shifts to rage or sadness
  • Irritability

How Common Are Mood Disorders?

As a group, mood disorders are one of the most common mental illnesses in the general population. Canadian studies looking at lifetime incidence of major depression found that 7.9% to 8.6% of adults over 18 years of age and living in the community met the criteria for a diagnosis of major depression at some time in their lives.1 Other studies have reported that between 3% and 6% of adults will experience dysthymia during their lifetime, 3 and that between 0.6% and 1% of adults will have a manic episode during their lifetime.4

During any 12-month period, between 4% and 5% of the population will experience major depression.1 According to the 1994/95 National Population Health Survey (NPHS), 6% of the Canadian population aged 12 years and over had symptoms consistent with depression at the time of the survey.5

Impact of Mood Disorders

Who Is Affected by Mood Disorders?

Mood disorders affect individuals of all ages, but usually appear in adolescence or young adulthood. However, late diagnosis is common: the average age of diagnosis of major depressive disorder is in the early twenties to early thirties.1

Studies have consistently documented higher rates of depression among women than among men: the female-to-male ratio averages 2:1.3 Women are 2 to 3 times more likely than men to develop dysthymia.

Sex differences in the symptoms associated with depression may contribute to the differences in the prevalence of depression between men and women. For example, men are more likely to be irritable, angry and discouraged when depressed, whereas women express the more "classical" symptoms of feelings of worthlessness and helplessness, and persistent sad moods. As a result, depression may not be as easily recognized in a man. In addition, women are more likely than men to seek help from health professionals. Biological or social risk or protective factors may also differ between men and women.

For bipolar disorder, it is generally accepted that the ratio between men and women is approximately equal.6

Ideally, data from a population survey would provide information on the age/sex distribution of individuals with mood disorders. Statistics Canada's Canadian Community Health Survey (CCHS) will provide this for 2002.

Although most individuals with mood disorders are treated in the community, hospitalization is sometimes necessary. At the present time, hospitalization data provide the best available, though limited, description of individuals with mood disorders. The results must be viewed with caution, however, since this is only a subset of those with mood disorders: most individuals with mood disorders are treated in the community rather than in hospitals, and many do not receive treatment at all.

In 1999, more women than men were hospitalized for major depressive disorder in every age group except 90+ years (Figure 2-1). Young women aged 15-19 years had much higher rates of hospitalization than the immediately adjacent age groups. Women between the ages of 40 and 44 years and men between the ages of 85 and 89 years had the highest rates of hospitalization for their sex.

Figure 2-1 Hospitalizations for major depressive disorder* in general hospitals per 100,000 by age group, Canada, 1999/2000

In 1999, in all except the 5-9 year age group, women were hospitalized for bipolar disorder at significantly higher rates than men (Figure 2-2). This contrasts with the generally accepted equal ratio of prevalence of the disorder among men and women. Further research is needed to explain this distribution. Women were most frequently hospitalized for bipolar disorder between the ages of 40 and 44 years.

Figure 2-2 Hospitalizations for bipolar disorder* in general hospitals per 100,000 by age group, Canada, 1999/2000

How Do Mood Disorders Affect People?

Because of their high prevalence, economic cost, risk of suicide and loss of quality of life, mood disorders present a serious public health concern in Canada. Depression and mania cause significant distress and impairment in social, occupational, educational or other important areas of functioning.7 According to the World Health Organization (WHO), major depression is the fourth leading cause of disability adjusted life years (DALYs) in the world.8 Major depression is the leading cause of years of life lived with disability (YLD) and bipolar is the sixth leading cause.8

Major depressive disorder is a recurrent illness with frequent episode relapses and recurrences. The more severe and longlasting the symptoms in the initial episode, due in some cases to a delay in receiving effective treatment, the less likely is a full recovery.

Unipolar major depressive disorder is identified as the fourth-ranked cause of disability and premature death worldwide.8 Depression also has a major impact on the mental health of family members and caregivers, often with an increased presence of depression and anxiety symptoms.

Dysthymia, as a result of its protracted nature, can be very debilitating.9 In spite of a high recovery rate, the risk of relapse is significant. Individuals with this disorder are also at high risk of experiencing an episode of major depression.10

Individuals with one episode of bipolar disorder tend to experience future episodes. Recovery rates vary among individuals. Those with purely manic episodes fare better than those with both mania and depression, who tend to take longer to recover and have more chronic course of illness.6

The mortality rate among individuals with bipolar disorder is 2 to 3 times greater than that of the general population, and includes higher rates of suicide.6

Child or spousal abuse or other violent behaviours may occur during severe manic episodes. Furthermore, individuals with bipolar disorder often show loss of insight, resulting in resistance to treatment, financial difficulties, illegal activities and substance abuse. Other associated problems include occupational or educational failure, financial difficulties, substance abuse, illegal activities and divorce.2 Individuals with bipolar disorder may often have difficulty maintaining steady employment and, as a result, may suffer social and economic disadvantages.

Mood disorders frequently accompany other mental illnesses, such as anxiety disorders, personality disorders, and substance abuse and dependencies. The presence of another mental illness increases the severity of the illness and results in a poorer prognosis. Individuals with mood disorders are at high risk of suicide.

Economic Impact

Because of their high prevalence, mood disorders have a major effect on the Canadian economy. This effect is dual in nature - first, with the associated loss of productivity in the workplace due to absenteeism and diminished effectiveness; and second, with the high health care costs attributable to primary care visits, hospitalizations and medication.

At the individual and family level, the loss of income and cost of medication create a strain on the family financial resources.

Stigma Associated with Mood Disorders

The stigma against individuals with mood disorders has a major influence in determining whether an individual seeks treatment, takes prescribed medication or attends counselling. This effect is greater among men than women. The stigma also influences the successful re-integration of the individual into the family and community.

Employers may be concerned that the individual with a mood disorder will be unable to function at the level of other employees. When the illness goes untreated, this may be true. However, with treatment to reduce or manage symptoms, performance usually improves. Reducing the stigmatization of mental illness in the workplace will be helped by increased knowledge and an employer's willingness and ability to respond appropriately to an employee's needs.11 Enforcement of human rights legislation can reinforce voluntary efforts.

Causes of Mood Disorders

Mood disorders have no single cause, but several factors, such as a biochemical imbalance in the brain, psychological factors and socio-economic factors, tend to make some individuals prone to such disorders.9,12

Genetic Influence

Studies have established that individuals with depression and bipolar disorder often find a history of these disorders in immediate family members.6,13 Evidence suggests that many different genes may act together and in combination with other factors to cause a mood disorder. Although some studies have suggested a few interesting genes or genomic regions, the exact genetic factors that are involved in mood disorders remain unknown.

Previous Episode of Depression

One episode of major depression is a strong predictor of future episodes. More than 50% of individuals who have an episode of major depression experience a recurrence.13

Stress

Stress has traditionally been viewed as a major risk factor for depression. Recent research efforts have indicated, however, that stress may predispose individuals only for an initial episode and not for recurring episodes.14 Responses to stress differ greatly among individuals: some are more susceptible than others to depression following life events, when they are in difficult relationships, or because of socio-economic factors such as inadequate income or housing, prejudice and workplace stress.

Physical Illness

A strong association exists between various chronic medical conditions and an elevated prevalence of major depression.15,16 Several conditions, such as stroke and heart disease, Parkinson's disease, epilepsy, arthritis, cancer, AIDS and chronic obstructive pulmonary disease (COPD), may contribute to depression. Several factors associated with physical illness may contribute to the onset or worsening of depression. These include the psychological impact of disability, decline in quality of life, and the loss of valued social roles and relationships. Medication side effects may also be a contributing factor. Finally, it is possible that the physical disease itself may contribute directly to the onset of depression by affecting physiological mechanisms such as neurotransmitters, hormones and the immune system; for similar reasons, episodes of mania may occur following physical illness or use of medications.

Indirect factors also influence the relationship between physical conditions and depression. Such factors include disability and quality of life of individuals with chronic disease and the tendency for some medications used for treating physical illnesses to cause depression.Treating chronic physical illness effectively requires vigilance for the early detection and treatment of depression.

Treatment of Mood Disorders

Mood disorders are treatable. Many people with a mood disorder fail to seek treatment, however, and suffer needlessly. Of those who seek treatment, many remain undiagnosed or receive either incorrect medication or inadequate doses.17 The delay in seeking and receiving a diagnosis and treatment may be due to a number of factors, such as stigma, lack of knowledge, a lack of human resources and availability or accessibility of services. Current initiatives to relieve the burden of mood disorders include not only improved recognition and use of effective treatments, but also education for individuals and families and for the community. Primary care settings play a critical role in both recognizing and treating these illnesses. Innovative practice models have shown that effective interventions can decrease symptoms and increase work days.18 Effective early treatment of mood disorders can improve outcomes and decrease the risk of suicide.

Antidepressant medications and education in combination with various forms of psychotherapy, such as cognitive-behavioural therapy, have demonstrated their effectiveness in treating depression. A recent publication from the Canadian Psychiatric Association outlines the clinical guidelines for the treatment of depressive disorders.1

Educating family and primary care providers is essential not only to ensure the recognition of early warning signs of depression, mania and suicide and to implement appropriate treatment, but also to ensure adherence to treatment in order to minimize future relapses. Sound support networks are crucial during both the acute phase of the illness and the post-illness adjustment to daily life.

Major depression results in poor productivity and sick leave from the workplace. The workplace, therefore, is an important area for addressing mental health issues. Supporting the development of healthy work environments, educating employers and employees in the area of mental health issues, and providing supportive reintegration into the work environment for those experiencing mental illness would go a long way toward minimizing the effect of major depression on the workplace.

Individuals with mood disorders may require hospitalization to adjust medication, to stabilize the disorder or to ensure protection against self-destructive behaviour.

Major Depressive Disorder

In 1999, among people under the age of 50 years with major depressive disorder who were hospitalized, the disorder was the main contributor to determining their length of stay (Figure 2-3). Among people with the disorder over the age of 50 years, depression was more likely to be an associated condition contributing to the length of stay. This is consistent with the association between physical illness and depression.

Figure 2-3 Hospitalizations for major depressive disorder in general hospitals per 100,000 by contribution to length of stay and age group, Canada, 1999/2000

Overall, between 1987 and 1999, hospitalization rates for major depressive disorder decreased by 33% among both men and women (Figure 2- 4).

Figure 2-4 Rates of hospitalization due to major depressive disorder* in general hospitals by sex, Canada, 1987/88-1999/2000 (age standardized to 1991 Canadian population)

Among women 25 years of age and over, rates of hospitalization due to major depressive disorder decreased between 1987 to 1997 while remaining fairly stable among women under the age of 25 years (Figure 2-5). Women over the age of 65 years showed the greatest rate of reduction.

Figure 2-5 Rates of hospitalization due to major depressive disorder* in general hospitals among women, Canada, 1987/88- 1999/2000 (age standardized to 1991 Canadian population)

Among both men and women aged 15 years and over, the wide variations in hospitalization rates that were evident in 1987 had disappeared by 1999, mostly as a result of moderate decreases in the 25-64 year age groups and the large decrease among those aged 65 years and over.

Among men, hospitalization rates for major depressive disorder between 1987 and 1999 showed the greatest decrease in the 65+ age group (Figure 2- 6). During this same time period, rates among young men aged between 15 and 24 years increased to a level similar to that of all older age groups.

Figure 2-6 Rates of hospitalization due to major depressive disorder* in general hospitals among men, Canada, 1987/88-1999/2000 (age standardized to 1991 Canadian population)

Between 1987 and 1999, the average length of stay in hospital in Canada due to major depressive disorder decreased by 20% (Figure 2-7).

Figure 2-7 Average length of stay in general hospitals due to major depressive disorder*, Canada, 1987/88-1999/2000

Bipolar Disorder

In 1999, bipolar disorder was the main contributor to the length of hospital stay among people with the disorder under the age of 50 years (Figure 2-8). Among older people, bipolar disorder was more likely to be an associated condition contributing to length of stay.

Figure 2-8 Hospitalizations for bipolar disorder in general hospitals per 100,000 by contribution to length of stay and age group, Canada, 1999/2000

Overall, hospitalization rates for bipolar disorders remained fairly stable among both men and women between 1987 and 1999 (Figure 2-9).

Figure 2-9 Rates of hospitalization due to bipolar disorder* in general hospitals by sex, Canada, 1987/88-1999/2000 (age standardized to 1991 Canadian population)

Between 1987 and 1999, hospitalization rates for bipolar disorder among women under the age of 25 years more than doubled (Figure 2-10). During the same period, rates in the older age groups decreased.

Figure 2-10 Rates of hospitalization due to bipolar disorder* in general hospitals among women, Canada, 1987/88-1999/2000 (age standardized to 1991 Canadian population)

Between 1987 and 1999, hospitalization rates for bipolar disorder among men aged 15-24 increased by 61%. Rates among men aged 25-44 years remained stable (Figure 2-11). Rates decreased by 14% among men aged 45- 64 years, and by 23% among men aged 65 years and over.

Figure 2-11 Rates of hospitalization due to bipolar disorder* in general hospitals among men, Canada, 1987/88-1999/2000 (age standardized to 1991 Canadian population)

Between 1987 and 1999, the average length of stay in general hospital due to bipolar disorder decreased by 27% (Figure 2-12).

Figure 2-12 Average length of stay in general hospitals due to bipolar disorder*, Canada, 1987/88-1999/2000

Discussion of Hospitalization Data

The higher hospitalization rates for depression among women than men support the clinical experience of higher rates of depression among women. Based on clinical research, rates of major depression among women are 2 times higher than among men. On the other hand, the hospitalization rates among women are only about 1.5 times higher than among men, suggesting that men may be hospitalized for major depression at higher rates than women. This requires further research for confirmation and explanation. Rates of bipolar disorder have been estimated to be equal among men and women. However, hospitalization rates for women with the disorder are much higher than men. Further research is required to assess if, in fact, rates of the disease are higher among women, or if women with the disorder are hospitalized at a higher rate than men, why this occurs.

Hospitalization rates for both depression and bipolar disorder among women peak between the ages of 35-49 years. Research is required to assess the factors in women's lives that contribute to this phenomenon.

Since 1987, hospitalization rates for depression among older Canadians have decreased much more than rates among younger age groups. Further research is required to determine the reasons for this trend. Has it been the result of better clinical treatment, and have outcomes for this age group also improved over this time period?

Hospitalization rates for bipolar disorder among young women and men have increased since the early 1990s. Does this signify an increase in bipolar disorder in these age groups, earlier recognition of the disorder, or a change in treatment?

Future Surveillance Needs

Mood disorders, including major depression, bipolar disorder and dysthymia are common and contribute to major personal and family distress. They also have a significant impact on workplace and health care costs.

Existing data provide a very limited profile of mood disorders in Canada. The available hospitalization data needs to be complemented with additional data to fully monitor these disorders in Canada. Priority data needs include:

  • Incidence and prevalence of major depression, bipolar disorder and dysthymia by age, sex and other key variables (for example, socio-economic status, education, and ethnicity).
  • Prevalence of depression in people with chronic physical illness.
  • Impact of mood disorders on the quality of life of the individual and family.
  • Access to and use of primary and specialist health care services.
  • Treatment outcomes.
  • Rates of suicide among individuals with mood disorders.
  • Access to and use of public and private mental health services.
  • Access and use of mental health services in other systems, such as schools, criminal justice programs and facilities, and employee assistance programs.
  • Impact of mood disorders on the workplace and the economy.
  • Stigma associated with mood disorders.
  • Exposure to known or suspected risk and protective factors.

References

  1. Canadian Psychiatric Association. Canadian clinical practice guidelines for the treatment of depressive disorders. Can J Psychiatry 2001;46:Supp1.
  2. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 4th edition. Washington, DC: American Psychiatric Association, 1994.
  3. Bland RC. Epidemiology of affective disorders: a review. Can J Psychiatry 1997;42:367-377.
  4. Kessler RC, McGonagle KA, Zhao S, Nelson CB, Hughes M, Eshleman S et al. Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Arch Gen Psychiatry 1994;51:8- 19.
  5. Stephens T, Joubert N. Mental health of the Canadian population: a comprehensive analysis.Chronic Diseases in Canada 1999:20:3 (www.hc-sc.ca/hpb/lcdc/publicat/cdic203/cd203c_e.html).
  6. Fogarty F, Russell JM, Newman SC, Bland RC. Mania. Acta Psychiatr Scand 1994;Suppl 376:16-23.
  7. Judd LL, Paulus MP, Wells KB, Rapaport MH. Socioeconomic burden of subsyndromal depressive symptoms and major depression in a sample of the general population. Am J Psychiatry 1996;153:1411-7.
  8. Murray CJL, Lopez AD, eds. Summary: The Global Burden of Disease: A Comprehensive Assessment of Mortality and Disability from Diseases, Injuries, and Risk Factors in 1990 and Projected to 2020. Cambridge, MA: Published by the Harvard School of Public Health on behalf of the World Health Organization and the World Bank, Harvard University Press, 1996. http://www.who.int/msa/mnh/ems/dalys/into.htm
  9. Horwath E, Weissman MM. Epidemiology of depression and anxiety disorders. In: Tsuang MT, Tohen M, Zahner GEP, eds. Textbook in Psychiatric Epidemiology. New York: Wiley-Liss, 1995:317-44.
  10. Klein DN, Schwartz JE, Rose S, Leader JB. Five-year course and outcome of dysthymic disorder: a prospective, naturalistic follow-up study. Am J Psychiatry 2000;157:931-9.
  11. Mintz J, Mintz LI, Arruda MJ, Hwang, SS. Treatments of depression and the functional capacity to work. Arch Gen Psychiatry 1992;49:761-8.
  12. Griffiths J, Ravindran AV, Merali, Anisman H. Dysthymia: a review of pharmacological and behavioral factors. Mol Psychiatry 2000;5:242-61.
  13. Spaner D, Bland RC, Newman SC. Major depressive disorder. Acta Psychiatr Scand 1994;Suppl 376:7-15.
  14. De Marco RR. The epidemiology of major depression: implications of occurrence, recurrence, and stress in a Canadian community sample. Can J Psychiatry 2000;45:67-74.
  15. Patten SB. Long-term medical conditions and major depression in the Canadian population. Can J Psychiatry 1999;44:151-7.
  16. Beaudet MP. Depression. Health Reports 1996;7(4):11-24.
  17. Bland RC. Psychiatry and the burden of mental illness. Can J Psychiatry 1998;43:801-10.
  18. Schoenbaum M, Un!tzer J, Sherbourne C, Duan N, Rubenstein LV, Mirand J et al. Costeffectiveness of practice-initiated quality improvement for depression: results of a randomized controlled trial. JAMA 2001;286:11:1325-30.

Wednesday, May 02, 2007

Chapter 1 Mental Illnesses In Canada : An Overview

From: Public Health Agency of Canada

Highlights

  • Mental illnesses indirectly affect all Canadians through illness in a family member, friend or colleague.
  • Twenty percent of Canadians will personally experience a mental illness during their lifetime.
  • Mental illnesses affect people of all ages, educational and income levels, and cultures.
  • The onset of most mental illnesses occurs during adolescence and young adulthood.
  • A complex interplay of genetic, biological, personality and environmental factors causes mental illnesses.
  • Mental illnesses can be treated effectively.
  • Mental illnesses are costly to the individual, the family, the health care system and the community.
  • The economic cost of mental illnesses in Canada was estimated to be at least $7.331 billion in 1993.
  • Eight-six percent of hospitalizations for mental illness in Canada occur in general hospitals.
  • In 1999, 3.8% of all admissions in general hospitals (1.5 million hospital days) were due to anxiety disorders, bipolar disorders, schizophrenia, major depression, personality disorders, eating disorders and suicidal behaviour.
  • The stigma attached to mental illnesses presents a serious barrier not only to diagnosis and treatment but also to acceptance in the community.

What Is Mental Illness?

Mental illnesses are characterized by alterations in thinking, mood or behaviour (or some combination thereof) associated with significant distress and impaired functioning over an extended period of time. The symptoms of mental illness vary from mild to severe, depending on the type of mental illness, the individual, the family and the socio-economic environment.

In the course of a lifetime, every individual experiences feelings of isolation, loneliness, emotional distress or disconnection at times. These are usually normal, short-term reactions to difficult situations, rather than symptoms of mental illness. People learn to cope with difficult feelings just as they learn to cope with difficult situations. In some cases, however, the duration and intensity of painful feelings or disorienting patterns of thought may interfere seriously with everyday life. Ordinary coping skills are overwhelmed, and people may need help in regaining balance and restoring their fullest functioning.

Mental health is as important as physical health to daily living. In fact, the two are intertwined. Individuals with physical health problems often experience anxiety or depression that affects their response to the physical illness. Individuals with mental illnesses can develop physical symptoms and illnesses, such as weight loss and blood biochemical imbalances associated with eating disorders. Feelings, attitudes and patterns of thought strongly influence people's experience of physical health or illness, and may affect the course of illness and the effectiveness of treatment.

Mental illnesses may occur together. An individual can experience both depression and an anxiety disorder, for example. In addition, attempts to manage symptoms through alcohol or drugs may contribute to substance abuse for some individuals. In one US study, 54% of those with a lifetime history of at least one mental illness also had at least one other mental illness or addiction to substances.1

Mental illnesses take many forms. This report includes:

  • Mood disorders
  • Schizophrenia
  • Anxiety disorders
  • Personality disorders
  • Eating disorders

A chapter on suicidal behaviour is also included because, while such behaviour is not in itself a mental illness, it is highly correlated with mental illness and raises many similar issues.

There are other significant mental illnesses (such as addictions) and issues surrounding special populations (such as children, the elderly and individuals with developmental delay). This report does not directly address these, but they will be the focus of future work. Nonetheless, the principles discussed in this overview apply to all mental illnesses.

How Common Are Mental Illnesses in Canada?

While in the past some regional population studies have investigated mental illness, recent national data on the prevalence of mental illnesses are lacking. Statistics Canada's Canadian Community Health Survey (CCHS), which is conducting a populationbased study on some mental illnesses, is expected to provide prevalence data in the near future.

Previous Canadian studies2,3 have estimated that nearly one in five Canadian adults will personally experience a mental illness during a 1-year period. Table 1-1 summarizes Canadian estimates of the prevalence of the mental illnesses included in this report. Based on estimates from the United States, personality disorders may affect 6% to 9% of the population.5

Table 1-1 Estimated One-Year Prevalence a of Mental Illnesses among Adults in Canada

Table 1-1 Estimated One-Year Prevalence a of Mental Illnesses among Adults in Canada

Impact of Mental Illnesses

Who Is Affected by Mental Illnesses?

Mental illnesses affect people in all occupations, educational and income levels, and cultures. The distribution is not random or uniform; some mental illnesses are more prevalent in some population groups. However, no one is immune, and at some point in their lives, all Canadians are likely to be affected through a mental illness in a family member, friend or colleague.

Ideally, data from a population survey would provide information on the distribution of mental illnesses by age, sex and other characteristics. Statistics Canada's CCHS will provide some of these data in the future. At the present time, hospitalization data provide the best available description of individuals with mental illness. These data have limitations, however, because most people with mental illness are treated in the community rather than in hospitals, and many do not receive treatment at all. Many factors other than the prevalence and severity of illness can influence hospital admissions and lengths of stay. These limitations must be kept in mind, then, when interpreting the data presented in this report.

According to hospitalization data, mental illnesses affect all ages. In 1999, rates among women were higher than among men in all age groups (Figure 1-1). Nearly one-half of all admissions for one of the seven most common mental illnesses involved individuals between the ages of 25 and 44 years. Canadians between 45 and 64 years accounted for onequarter (24%) of hospitalizations. The high rates of hospitalization among young adults aged between 15 and 24 years attest to the impact of mental illnesses on young people.

Figure 1-1 Rates of hospitalization for one of seven mental illnesses* in general hospitals per 100,000 by age and sex, Canada, 1999/2000

Overall, the conditions discussed in this report accounted for 3.8% of all general hospital admissions in 1999 (as the primary or most responsible diagnosis). The proportion among both men and women in the 15-24 and 25- 44 year age groups was much higher, however: over 10% (Figure 1-2).

Figure 1-2 The proportion of all hospitalizations that are due to one of seven mental illnesses* in general hospitals by age and sex, Canada, 1999/2000

Although 1999 general hospital admission rates among women aged 65 years and over were much lower than among women aged 45 to 64 years, the days rate of hospitalization was almost the same (Figure 1-3). Hence, the older group stayed longer in hospital.

Figure 1-3 Days of hospitalization for one of seven mental illnesses* in general hospitals (number of days spent in hospital) per 100,000 by age and sex, Canada, 1999/2000

How Do Mental Illnesses Affect People?

The onset of most mental illnesses occurs during adolescence and young adulthood. This affects educational achievement, occupational or career opportunities and successes, and the formation and nature of personal relationships. The effect extends throughout an individual's life. The greater the number of episodes of illness that an individual experiences, the greater the degree of lasting disability. Receiving and complying with effective treatment and having the security of strong social supports, adequate income, housing and educational opportunities are essential elements in minimizing the impact of mental illness.

In developed countries, mental illnesses (major depression, bipolar disorder, schizophrenia, and obsessive-compulsive disorder) account for four of the 10 leading causes of disability.6

Suicide is a significant risk for individuals with some mental illnesses, such as major depression, bipolar disorder, schizophrenia and borderline personality disorder.

Mental illnesses have a significant impact on the family. To begin with, they may face difficult decisions about treatment, hospitalization, housing and contact with the family member with mental illness. The individuals and their families face the anxiety of an uncertain future and the stress of what can be a severe and limiting disability. The heavy demands of care may lead to burnout. Families sometimes fear that they caused the illness. The cost of medication, time off work, and extra support can create a severe financial burden for families. Both the care requirements and the stigma attached to mental illness often lead to isolation of family members from the community and their social support network and may even contribute to the suicide of a family member.

Economic Impact

Mental illnesses also have a major impact on the Canadian economy in terms of productivity losses and health care costs. Measuring the economic impact of mental illnesses in Canada faces the challenge of a lack of comprehensive data on not only the use and cost of services, but also the economic impact of lost productivity through, for example, absence from work.

A 1993 study by Health Canada used several types of administrative and survey data, including physician billing data, hospitalization data, and data on selfreported activity restriction to estimate the cost of mental illnesses at $7.331 billion in 1993 dollars.7 Some costs, such as loss of productivity by those too ill to complete surveys, could not be captured through the available data.

A later Canadian study drew upon the same data as well as data from the 1996/97 NPHS questions regarding depression and distress and self-reported use of health services; the authors estimated that the annual economic impact of mental health problems in Canada is $14.4 billion.8 The authors of this study also believe the figure to be an under-estimate due to the limitations of their dataset.

While estimates will vary widely depending on what costs are included, it is clear that the economic burden of mental illnesses is enormous.

Mental illnesses are a major contributor to hospital costs. According to the Canadian Institute for Health Information (CIHI), Canadian hospitals reported 199,308 separations related to mental illness in 1999/2000. General hospitals accounted for 86% and provincial psychiatric hospitals for 14%. In 1999/2000, 9,022,382 hospital days were utilized by individuals with mental illnesses. These were almost equally distributed between provincial psychiatric and general hospitals. The overall average length of stay was 45 days. The average length of stay in psychiatric hospitals was 160 days compared to 27 days in general hospitals.

Stigma and Discrimination Associated with Mental Illnesses

The serious stigma and discrimination attached to mental illnesses are among the most tragic realities facing people with mental illness in Canada. Arising from superstition, lack of knowledge and empathy, old belief systems, and a tendency to fear and exclude people who are perceived as different, stigma and discrimination have existed throughout history. They result in stereotyping, fear, embarrassment, anger and avoidance behaviours. They force people to remain quiet about their mental illnesses, often causing them to delay seeking health care, avoid following through with recommended treatment, and avoid sharing their concerns with family, friends, co-workers, employers, health service providers and others in the community.

The Canadian Alliance for Mental Illness and Mental Health (CAMIMH) has identified combating the stigma of mental illnesses and preventing discrimination against people with mental illnesses as one of the most pressing priorities for improving the mental health of Canadians. Educating the public and the media about mental illness is a first step toward reducing the stigma and encouraging greater acceptance and understanding of mental illness. Developing and enforcing policies that address discrimination and human rights violations provides incentives for change.

Causes of Mental Illnesses

Research suggests that mental illnesses are the result of a complex interaction of genetic, biological, personality and environmental factors; however, the brain is the final common pathway for the control of behaviour, cognition, mood and anxiety. At this time, the links between specific brain dysfunction and specific mental illnesses are not fully understood.9 In the chapters that follow reference is frequently made to both genetic endowment (e.g. inherited dysfunctions affecting brain chemistry) and the environment (e.g. external physical and psychosocial factors) when discussing the causes, treatment and prevention of mental illnesses. It is important not to over-interpret the available evidence about the role of either genetic or environmental factors in causing mental illnesses as much more research is needed to fully understand the cause of mental illness.

Most mental illnesses are found to be more common in close family members of a person with a mental illness, suggesting a genetic basis to the disorders. In some instances there is research evidence suggesting that particular genetic factors affecting brain chemistry contribute to the onset and progression of mental illness. However, there is also increasing evidence that long-term changes in brain function can occur in response to factors in the environment such as stimulation, experiences of traumatic or chronic stress, or various kinds of deprivation. In other words, the interaction between brain biology and lived experience appears to work both ways.

For reasons that may be biological, psychosocial, or both, age and sex affect rates of mental illness. Environmental factors such as family situation, workplace pressures and the socio-economic status of the individual can precipitate the onset or recurrence of a mental illness. Lifestyle choices (e.g. substance abuse) and learned patterns of thought and behaviour can influence the onset, course and outcome of mental illness.

The interaction of physical and mental illness is similarly complex. There is evidence that mental illness can contribute to, result from, or share a common causal pathway with, physical illnesses such as cancer, heart disease and chronic obstructive pulmonary disease (COPD).

Since a great deal remains unknown about the respective roles and interactions of heredity and environment, brain dysfunction and lived experience, it is prudent to give them equal consideration.

Poverty and Mental Illnesses

The relationship between poverty and mental illnesses is complicated. Many studies have found that socio-economic status is inversely related to the development of mental illness. Two frameworks10 have been proposed to explain this relationship.

Indirect Association: Selection and Drift

The concept of selection proposes that certain individuals may be predisposed both to a mental illness and to lower expectations and ambition. These in turn, result in lower levels of educational and occupational achievement. On the other hand, milder undiagnosed mental illness makes it difficult for individuals to succeed in the complex post-industrial society. Poverty is associated with a lower level of achievement in formal education. In this situation, then, there is an indirect association between poverty and mental illness.

"Drift" refers to the likelihood that those with a mental illness may drift into poverty as they have difficulty achieving and maintaining regular employment. This indirect association between poverty and mental illness may be mitigated by the "class" effect, whereby the networks of support around people in higher socio-economic classes prevent their drift into poverty.

Direct Association: Social Causation

Direct association between poverty and mental illness implies that the social experience of individuals who are poor increases the likelihood that they may develop a mental illness. For example, living in poverty may lead to a lack of opportunity and consequently to hopelessness, anger and despair. Poverty may also increase the risk of exposure to chronic or traumatic stress. When combined with a genetic predisposition, such factors may contribute to the development of mental illnesses. However, it is important to note that most people who are poor do not have mental illnesses. This suggests that if there is social causation, it involves additional factors.

Prevention and Treatment

Addressing the psychological and social determinants of mental health can promote mental health and perhaps prevent some mental illnesses.

At the level of the individual, such factors as secure attachment, good parenting, friendship and social support, meaningful employment and social roles, adequate income, physical activity, and an internal locus of control will strengthen mental health and, indirectly, reduce the impact or incidence of some mental health problems.

At a system level, strategies that create supportive environments, strengthen community action, develop personal skills and reorient health services can help to ensure that the population has some control over the psychological and social determinants of mental health.

Primary prevention of most mental disorders is still in early stages of development. Given the very consistent evidence that a history of severe trauma (such as physical or sexual abuse) is correlated with various mental health problems (dissociative disorders, personality disorders, addictions, post traumatic stress disorder (PTSD))11,12, it is reasonable to conclude that preventing such traumas would prevent mental health problems. There is promising evidence that early teaching of cognitive-behavioural strategies can prevent or reduce the impact of anxiety disorders.13

Most mental illnesses can be treated. Treatment must reflect the complex origins of mental illnesses. A variety of interventions, such as psychotherapy, cognitive behavioural therapy, medication, occupational therapy and social work, can improve an individual's functioning and quality of life. Since mental illnesses involve disorders of brain functioning, medication often forms an important part of treatment.

Making the correct diagnosis and tailoring effective treatment to the individual's needs are essential components of an overall management plan. The active involvement of the individual in the choice of therapy and his/her adherence to the chosen therapy are critical to successful treatment. Sometimes, protecting the health of the individual may require the involvement of alternative decision-makers.

Treatment requires a variety of health and social service providers and volunteers organized into a comprehensive system of services. Service providers need to work as a team to ensure continuity of care. For maximal effectiveness, a treatment system should provide all individuals with access to services where needed. When adequately resourced, treatment in the community has many advantages. The reforms of the mental health system of the 1960s and 1970s reduced the number beds in psychiatric institutions. Many individuals with a mental illness moved from chronic care facilities back into the community. Communities have faced major challenges in helping not only these individuals, but also those newly diagnosed with severe mental illness, to create a reasonable quality of life in the community.14

Towards a Comprehensive System

There are many perspectives on what would constitute a comprehensive, effective mental health care system. The following are a number of elements that could be regarded as essential to such a system.

Education for Users of Services and Their Families

Individuals and families directly affected by mental illness need information about the signs and symptoms of these illnesses, sources of help, medications, therapy and early warning signs of relapse. Booklets, videotapes and family consultations can help to raise awareness. Outcomes may be improved by educating people in order to enhance their abilities to identify episodes in the earlier stages and to respond with appropriate actions.

Community Education

Dispelling the myths surrounding mental illness requires community education programs, including programs in schools. Such programs could help to reduce the stigma associated with mental illness and improve the early recognition of a problem. They may also be instrumental not only in encouraging people to seek care but also in creating a supportive environment for the individual.

Self-Help/Mutual Aid Network

Self-help (mutual aid) organizations and programs connect individuals to others facing similar challenges and provide support to both individuals and family members. Mutual aid groups have been found to empower individuals, in particular by providing information, reducing isolation and teaching coping skills. They can work in effective partnerships with professional services if their strengths are recognized and the boundaries between formal health care and mutual aid are acknowledged.

Primary and Specialty Care

For most Canadians, the primary care physician is their first and often only contact with the health care system. Under-diagnosis, misdiagnosis and under-treatment of mental illness can result in poor outcomes. As a result, educating primary care physicians to properly recognize, diagnose and treat most mental illnesses, and to know when to refer the affected individuals to others, has a crucial role in maximizing the care that they provide. Training of family medicine residents in these topics is also essential. Creating and distributing consensus treatment guidelines is a first step to increase knowledge about mental illnesses, their diagnosis and treatment. Encouraging the use of these guidelines requires attention to the predisposing, enabling and reinforcing factors that exist in the clinical setting.

In the Shared Care Model of mental health care delivery,15 psychiatrists and mental health professionals work with family physicians, providing support and counselling assistance in the daily clinic setting. Care providers and individuals requiring service have found this to be an effective model.

Other health professions, such as psychology and social work, also provide essential services to those with mental illness. An ideal primary care model would involve psychologists, social workers, family physicians, psychiatrists, nurses, pharmacists and others working in a collaborative and integrated system.

Hospitals

The hospital emergency department is a valuable resource for crisis interventions and may be an individual's first point of contact with the health care system. However, an ideal system would incorporate a more comprehensive crisis response system (see next section).

Hospitalization for a mental illness can assist in the diagnosis and can stabilize symptoms. It can provide a critical respite from the sometimes overwhelming challenges of daily living. The hospital also serves as a safe and supportive environment when the risk of suicide is high or judgement is severely compromised by the presence of mental illness. Ideally, multidisciplinary teams of physicians, nurses, occupational therapists, pharmacists, social workers and case managers work with the individual and family to identify and respond to the factors that influence symptoms. They also assist the individual and family in understanding and coping with their personal responses to the mental illness.

Although hospitalization provides important short-term respite and care, prolonged periods in hospital remove individuals from their normal environment and can weaken social connections, making re-integration into community living more challenging. Planning for the person's transition back into community living is an important role of the hospital team, which should be carried out in cooperation with care providers and service agencies in the community. An investment in community outreach programs, which support individuals in living productive, meaningful, and connected lives, is an essential cost-effective complement or alternative to hospital-based care.

Hospital-based programs targeted at improving independent living skills can help individuals acquire social, communication and functional living skills that improve their ability to cope with the demands of living.

Crisis Response Systems / Psychiatric Emergency Services

Many persons with severe mental illness are vulnerable to stress and face recurrent episodes of psychosis. Others experience crises due to poverty, recurrent unemployment, loss of housing or loss of support networks. Despite the differing origins and manifestations of these crises, hospital emergency rooms have been the primary venue for crisis management. Unfortunately, adequate follow-up has been difficult to ensure, and crisis prevention and early intervention are not addressed. Opportunities to link new users to appropriate resources, or to mobilize existing networks to help manage crisis situations, are missed.

Crisis response systems (CRS) have been proposed to provide a more effective approach. Rather than a single service response, a CRS encompasses a range of services integrated across various providers. With its expertise and range of options, a CRS is positioned to resolve crises using minimally intrusive options, particularly for noncompliant persons. A CRS offers backup to community providers, including mental health personnel, family practitioners and police; it provides an important community outreach mechanism by connecting first time users to appropriate services; and it serves as a valuable community relations tool by reassuring members of the community, such as landlords, that persons with severe mental illness will be supported during crises.

Crisis-specific functions include:

  • Medical services, including inpatient services when other options have been exhausted;
  • Short-term residential placements for crisis stabilization in protective and supportive settings;
  • Mobile crisis outreach which brings assistance to virtually any site in the community where crisis is occurring;
  • Walk-in crisis intervention services; and
  • Telephone crisis services.16

Case Management / Community Outreach Programs

Case management programs (sometimes referred to as community outreach) come in many forms, but generally consist of multidisciplinary teams that share the clinical responsibility for each individual receiving care in the community. A team aims to help individuals with mental illness to achieve the highest level of functioning possible in the least restrictive setting. To this end the team works to ensure compliance with treatment (particularly for those with schizophrenia and other psychotic illnesses) and, consequently, improve functioning in order to reduce the need for hospital readmission. The program also focuses on obtaining and coordinating needed services from a variety of health and social agencies; resolving problems with housing, employment, leisure, relationships and activities of daily living; and providing social skills training to improve social functioning.

Key features of good case management include:

  • A caring, supportive relationship between the team and the individual; and
  • Emphasis on flexibility and continuity of care - that is, supports provided as long as needed, across service and program settings, even when the person's needs change over time.

A model of case management that has been positively evaluated is Assertive Community Treatment (ACT). The ACT team has a high staff/patient ratio and provides the individual with access to support when and where needed - 24 hours a day, 7 days a week. An individual who is at high risk of relapse and hospitalization needs this type of support, especially when family or social support is limited.17

Workplace Supports

Aside from the home, the workplace is the primary location of adult life. As such, it plays an influential role in an individual's health and well-being. Much of the impact of mental illnesses in the workplace is reflected in poor productivity and increased use of sick leave. Stigma surrounds people with mental health difficulties, and the recovery process is often misunderstood. Employers need to demonstrate that they do not discriminate and are fair in their policies and procedures in dealing with mental health problems.18

The workplace has great potential to develop and maintain a healthy work environment by educating employers and employees in the area of mental health issues and providing supportive reintegration into the work environment for those experiencing mental illness. Vocational rehabilitation supports permanent competitive employment - that is, the ability to hold a regular job in the community.

It is important to address the high levels of unemployment and poverty found among people with mental illness and to support their desire for work. Consumer/survivor-run businesses have proven effective in restoring employment to individuals with mental illnesses.

Other Supports

A variety of other programs and services - such as long-term care residences, community rehabilitation, special needs groups, specialty services (sleep laboratory, psycho-pharmacological consultation), and community crisis centres - can contribute to the diagnosis, treatment and integration of individuals into the community and the improvement of their quality of life. Other supports are required to ensure adequate income, safe housing and opportunities for regular education for these individuals with mental illnesses.

The Best Practices in Mental Health Reform documents produced under the aegis of the Federal/Provincial/Territorial Advisory Network on Mental Health provide more detailed information and recommendations about specific components of a comprehensive, effective mental health care and support system. They also discuss system-wide strategies that foster the widespread implementation of effective services and supports for people with serious and chronic mental illness. These documents are available on Health Canada's web site at: http:// www.hc-sc.gc.ca/hppb/mentalhealth/ service_systems.htm

Future Directions

As a group, mental illnesses present an important public health challenge for Canada. All sectors of society and all levels of government have roles to play in responding adequately to this challenge. The Canadian Alliance for Mental Illness and Mental Health (CAMIMH), a coalition of non-governmental organizations that includes representation from the voluntary, professional, consumer and family sectors, has proposed a national action plan to guide the national response to mental illnesses. (See Appendix B.) CAMIMH views this as a blueprint that will be expanded upon and further developed in collaboration with other stakeholders.

A health problem of the scope and importance of mental illness requires a comprehensive surveillance system to monitor progress in achieving the goals of the national action plan. A workshop held in September 1999, co-sponsored by Health Canada and CAMIMH, developed a comprehensive indicator framework for a Mental Illnesses and Mental Health Surveillance System. This report responds to the recommendations from the workshop to collate existing data in order to begin the process of creating a picture of mental illness in Canada.

As will be seen in the following chapters, hospitalization and mortality data provide a partial picture of mental illness in Canada. Since most people do not die from mental illnesses and most care is provided outside of the hospital setting, however, the information that these data provide is limited. Concern also exists about the quality and the scope of the hospitalization and mortality data.

The CCHS-Cycle 2 - Mental Illnesses Survey, to be completed by Statistics Canada in 2003, will provide new data on mental illnesses, including prevalence, quality of life, stigma and the use of health services.

The Development of Indicators for Mental Health and Addiction Service project at the Canadian Institute for Health Information (CIHI) will provide a report on inpatient hospital indicators that could be calculated using existing data.

The linking of provincial databases, such as physician billing, hospitalization, pharamacare and mortality, would also provide valuable information for a mental illness surveillance system. In all steps to improve surveillance, the protection of private information is a critical concern.

While the future holds the promise of improved data for mental illness surveillance in Canada, much more needs to be done. Each chapter in this report focuses on a specific mental illness or group of disorders, using existing hospitalization data and identifying priority data needs for surveillance. The collection, analysis and dissemination of this data will then serve to guide decisions in policies and services aimed at improving the quality of life of people who live with mental illnesses.

Resources

A list of Web-sites of national organizations for mental illnesses.

Alzheimer Society of Canada: www.alzheimer.ca

Canadian Association for the Mentally Ill: www.cami.org

Canadian Association of Social Workers: www.casw-acts.ca

Canadian Health Network: www.canadian-health-network.ca/1mental_health.html

Canadian Institute for Health Information: www.cihi.ca

Canadian Institutes of Health Research - Institute of Neurosciences, Mental Health and Addiction: www.cihr-irsc.gc.ca/institutes/inmha

Canadian Medical Association: www.cma.ca

Canadian Mental Health Association: www.cmha.ca

Canadian Psychiatric Association: www.cpa-apc.org

Canadian Psychiatric Research Foundation: www.cprf.ca

Canadian Psychological Association: www.cpa.ca

Centers for Disease Control and Prevention: www.cdc.gov

Centre for Addiction and Mental Health: www.camh.net

The College of Family Physicians of Canada: www.cfpc.ca

Health Canada, Mental Health: www.hc-sc.gc.ca/hppb/mentalhealth/mhp/index.html and www.hc-sc.gc.ca/english/lifestyles/mental_health.html

The Mood Disorders Society of Canada: www.mooddisorderscanada.ca

The National Eating Disorder Information Centre: www.nedic.ca

National Network for Mental Health: www.nnmh.ca

Schizophrenia Society of Canada: www.schizophrenia.ca

Statistics Canada: www.statscan.ca

Canadian Association of Occupational Therapists: www.caot.ca/index.cfm

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  10. Eaton WW, Muntaner C. Socioeconomic stratification and mental disorder. Horwitz AV, Sheid TL, ed., "A Handbook for the Study of Mental Health - Social Context, Theories and Systems, (Ch. 14). Cambridge University Press, 1999: 259.
  11. Rosenberg SD, Drake RE, Mueser K. New directions for treatment research on sequelae of sexual abuse in persons with severe mental illness. Community Ment Health J. 1996 Aug;32(4):387-400.
  12. Leverich GS, McElroy SL, Suppes T, Keck PE, Denicoff KD, Nolen WA, Altshuler LL et al. Early physical and sexual abuse associated with an adverse course of bipolar illness. Biol Psychiatry 2002 Feb 15;51(4):288- 97.
  13. Dadds MR, Spence SH, Holland DE, Barrett PM, Laurens KR. Prevention and early intervention for anxiety disorders: a controlled trial. J Consult Clin Psychol 1997;65:627-35.
  14. Canadian Alliance on Mental Illness and Mental Health. A Call for Action: Building Consensus for a National Plan on Mental Illness and Mental Health, 2000.
  15. Kates N. Shared mental health care: the way ahead. Can Fam Physician, 2002 May;48:853-5.
  16. Adapted from "Crisis response systems/psychiatric emergency services," in Review of Best Practices in Mental Health Reform, Federal/Provincial/Territorial Advisory Committee on Mental Health, 1997, available online at http://www.hc-sc.gc.ca/hppb/mentalhealth/pubs/bp_review/e_index.html.
  17. For more information about case management and ACT, see "Case management/assertive community treatment" in Review of Best Practices in Mental Health Reform, Federal/Provincial/Territorial Advisory Committee on Mental Health, 1997, available online at http://www.hc-sc.gc.ca/hppb/mentalhealth/pubs/bp_review/e_index.html.
  18. Gabriel P, Liimatainen M. Mental Health in the Workplace. Geneva: International Labour Office, 2000.

Tuesday, May 01, 2007

No Health Without Mental Health

Part 1 - Mental Health Promotion for People with Mental Illness
From: The Canadian Health Network

Good health means having both good physical and good mental health. This is the first in a two-part series on mental health promotion, an umbrella term for strategies and activities aimed at having a positive effect on mental health. Part One explores mental health promotion for people with mental illness and Part Two, to be published on May 15th, shows how promoting mental health is good for us all.

  • A group of mental health consumers gathers in North Bay, Ontario, for a training session about WRAP: a Wellness Recovery Action Plan designed to help them recognize signs of a relapse, and teach them techniques to help prevent them from becoming seriously ill again.


  • In Medicine Hat, Alberta, the coordinator of a program that helps people with a mental illness find and keep mainstream employment speaks with patients at the regional hospital psychiatric ward about how the program can work with their wellness plan.


  • At a meeting of a mental health consumer support group in Sudbury, Ontario, a valued board member's resignation is applauded when his peers learn the reason: the demands of his new job as a supervisor at a large company.

You might conclude that the common thread in all these scenarios is mental illness. That is true, but it's only one strand of a richly woven fabric. What links these people is that, in each situation, mental health promotion is at work, providing a range of supports and resources that help people with a mental illness gain control over their lives and build the resilience they need to cope and move forward.


What is mental health promotion (MHP)?

But what exactly is mental health promotion? Ask five Canadians, and chances are you will hear five different responses. Some people think it refers to public awareness and education campaigns. Others believe it means programs, while others see it more as a philosophy. The definition of MHP varies even among organizations that have a mandate to assist people with a mental illness or a mental health problem.

In fact, MHP encompasses all these elements and includes many key principles of health promotion theory and practice. In 1986, the Ottawa Charter on Health Promotion, produced by the World Health Organization, defined health promotion as "the process of enabling individuals and communities to increase control over the determinants of health and thereby improve their health."

This definition does not separate out people with a mental illness. "Mental illness and mental health are not mutually exclusive," points out Bonnie Pape, former Director of Programs for the Canadian Mental Health Association National office (CMHA). "People don't always understand that you can have an illness and at the same time have health." For example, a person with bipolar disorder can, with the help of treatment, learn coping skills that enable them to maintain healthy relationships and employment. The symptoms remain, but their effects on a person's quality of life can be reduced.


Mental illness in Canada – a growing concern

Mental illness affects all Canadians at some time, indirectly through a family member, friend or colleague, or directly through personal experience.

  • One in five Canadians will develop a mental illness at some time in their lives


  • Mood disorders affect an estimated 10% of Canadians


  • Anxiety disorders affect approximately 12% of Canadians


  • Stress and mental health-related problems represent 40-50% of the short-term disability claims among employees of some of Canada's largest companies


  • In 1998, the total value of lost work time in Canada due to depression was $2.16 billion. The total economic burden of mental disorders was $14.4 billion.

Mental health promotion builds on strengths

For people with a mental illness, MHP focuses on a person's abilities and capacities to enhance strength, resilience and self-confidence. Effective MHP involves strengthening people's coping skills, and above all, their ability to take control over their lives, thereby improving their mental health.

Since mental health promotion applies to everyone in society, it follows that its ripple effect touches all aspects of our lives. The benefits of MHP include:

  • improved well-being
  • enhanced networks of social support
  • greater social inclusion
  • reduced stress
  • better understanding of the needs and experience of people with mental illness.

Mutual support is key

Social inclusion is a recurring theme in any discussion about MHP. Ask Ellen Cohen why she is so passionate about the consumer/survivor network she helped create and she says simply: "It stopped the isolation." The North East Ontario Consumer Survivor Network (NEON) has 200-300 members, meets on a quarterly basis and offers peer support and training opportunities.

"It was very isolating when you didn't have a peer group to share with," says Ellen, NEON's North East Regional Coordinator. "People may be frustrated by developing their own organization, they might get mad and need a place to vent, but at the same time they're learning coping skills, they're learning skills to deal with conflict, to develop something positive."

NEON may have been launched with peer support as its primary goal, but that has since grown into skill development initiatives, such as WRAP and suicide/crisis prevention, as well as participation in the regional awareness campaign, We All Belong.

"Mutual support, to me, is just about the best example of MHP going," says Bonnie Pape. "Instead of being a recipient of services in an illness model, people are providers of health to one another and they're identifying their capacities and strengths and what they're good at."


A practical tool kit for communities

Mental health promotion is a positive approach to positive mental health. In the Mental Health Promotion Tool Kit, developed by CMHA, MHP is described as "any actions which are taken for the purpose of fostering, protecting and improving mental health."

From posters about depression to community-level advocacy for improved housing, from skills training to peer support groups – if improved mental health is the goal of any initiative, it qualifies as mental health promotion.


Mental health promotion helps people find jobs

Routes to Work, an initiative of CMHA National, started as a one-year program in 1996. Since then, it has expanded to seven sites across Canada, and has helped over 300 people with mental illness to gain employment, and over 425 to enhance their employability.

Employment has been identified as one of the prime determinants of health. As a source of money, social contacts and identity, work has a huge impact on our physical and mental health.

"Routes to Work fits the person to the job and offers so much support along the way," says Julie Flatt, Program Manager. Julie credits Routes' employment support workers (ESW's) for a tremendous amount of mental health promotion, especially in the area of public education. "Our ESW's sensitize people to the fact that mental illness is not a distant thing any more," says Julie. "It opens them up to the fact that maybe their workplaces have to change."

Sarah Carleton, a Routes to Work ESW in Kingston, Ontario, develops her portfolio of potential employers through meetings and by holding workshops about mental illness. "I try to demystify people with mental illness in the workplace," she says. Recently, banks, in particular, have demonstrated a willingness to accommodate diversity. "They've been open to offering interviews with my clients," she says. 'They're pretty educated about mental illness."

In Medicine Hat, Alberta, Routes to Work coordinator Duncan Dyer makes sure other community agencies know all about the program. "We're fortunate in having a really cohesive network," he says. "Most of our clients are referred by other agencies."

At NEON in northern Ontario, some members have found mainstream employment. "These are valuable people that were so beaten and so ill," says Ellen. "They were told they'd never be able to work, that they would always be on drugs, and now they're out and as a result of being involved in a consumer organization, many have become coordinators, executive directors, staff and peer support members."


Mental health promotion benefits everyone

"When we talk about the benefits of MHP for people with a mental illness, we use terms like recovery - and this is not like recovering from the flu, it's having the feeling that you can get on with your life, that you can cope," says Bonnie Pape. "The things people say contribute to their recovery are very similar to how we understand MHP: inclusion, feeling accepted, that someone believes in you."

And that leads to believing in oneself, like when members of NEON participated in the regional awareness campaign, We All Belong, from 2001-2005. They made presentations and held workshops across northern Ontario, and as they informed their communities about mental illness, their pride grew. "You could see people getting strong," says Ellen Cohen. "These were unexpected results, how it empowered people, how it made people well."